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Learn · Testosterone, Estrogen & Binding

Estriol (E3)

Measured in pg/mL

The weakest of the three estrogens, and the one that dominates in pregnancy. Outside pregnancy it is a minor player, measured to complete the estrogen picture in a full female work-up.

What the numbers mean

These are the ranges BioForge works to. They are not the same as a lab's reference range, which is built from the general population rather than from people who feel well.

Low
— · Not a deficiency state
Optimal
<80 · Non-pregnant adults
High
>80 · Pregnancy or estriol cream

What moves Estriol (E3)

Rises by orders of magnitude in pregnancy — where it is measured in ng/mL, not pg/mL — and with compounded estriol creams. Outside those two situations it stays near the floor, and a low result is normal rather than a deficiency to correct.

Related markers in Testosterone, Estrogen & Binding

This page is educational and is not medical advice. Ranges are general and do not account for your history, medications or symptoms — a single number never decides a protocol. Your results are interpreted by a licensed clinician alongside everything else about you. Back to the Learning Center

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